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Cystic Fibrosis

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Cystic Fibrosis

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There are different types of mutations affecting the proper functioning of the CFTR channels. Hence, depending on the type of mutation, the manifestation of the disorders can vary between individuals. Different studies suggest that improper functioning of the CFTR channels in CF patients is the malfunctioning of organs such as the lungs, alongside the digestive system; nevertheless, new studies also shows that it can impact the heart functioning as well as the reproductive system.   1. In relation to the CFTR channels’ malfunctioning in a CF patient, how can this malfunctioning affect the embryo’s lung development? (30 pts).    2. In relation to the CFTR channels’ improper functioning in CF patient, how this malfunctioning can affect the digestive system? Please discuss the development of the digestive system and the role of CFTR in the proper functioning (30 pts)   Articles such as these below, will help give an idea of what I’m asking for.   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052671/pdf/12931_2018_Article_834.pdf   https://www.dldjournalonline.com/article/S1590-8658(14)00424-1/fulltext

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